Abstract
Vasomotor activity of the major and cerebral arteries was studied in mice with chronic obstructive pulmonary disease. Regional differences were revealed in the endothelium-dependent response of arteries. The development of chronic obstructive pulmonary disease was associated with a paradoxical response of the dilatational component of vasoregulation against the background of increased constrictive influences of the vascular endothelium in the major and cerebral vessels.
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References
V. N. Anan’ev, B. N. Manukhin, and O. V. Anan’eva, Adrenoreactivity and Cholinoreactivity of Systemic and Regional Blood Supply during Cold Adaptation [in Russian], Moscow (2002).
V. I. Bobrova, Nervous System and Chronic Obstructive Pulmonary Diseases with Systemic Arterial Hypertension [in Russian], Kiev (2001).
T. A. Brodskaya, V. A. Nevzorova, B. I. Geltser, and E. V. Motkina, Ter. Arkhiv, No. 3, 76–84 (2007).
B. I. Geltser, V. N. Kotelnikov, I. G. Agafonova, and P. A. Luk’yanov, Byull. Eksp. Biol. Med., 140, No. 11, 587–591 (2005).
B. I. Geltser, S. V. Savchenko, V. N. Kotelnikov, and I. V. Plotnikova, Kardiologiya, No. 4, 24–28 (2004).
T. Yu. Demidova, A. S. Ametov, and L. V. Smagina, Klin. Med., No. 10, 25–30 (2005).
N. A. Manak, I. A. Kozich, and I. S. Karpova, Kardiologiya SNG, No. 5, 26–29 (2003).
P. A. Motavkin, Regulation of Cerebral Blood Flow [in Russian], Vladivostok (1992).
E. V. Motkina and V. A. Nevzorova, Tikhook. Med. Zh., No. 2, 34–37 (2005).
N. N. Fedosova, V. N. Tsyuryupa, and I. V. Vlasova, Ul’trazvuk Funkts. Diagnost., No. 3, 72–77 (2005).
O. V. Filatova, V. D. Kiselev, O. V. Trebukhov, and L. D. Kozlova, Ros. Fiziol. Zh., No. 12, 1503–1511 (1999).
A. Agusti and T. A. Neff, Proceedings of the ATS, 3, No. 6, 478–481 (2006).
T. S. Shim, J. H. Lee, S. Y. Kim, et al., Chest, 120, No. 5, 1506–1513 (2001).
M. J. Van de Ven, W. N. Colier, M. C. Van der Sluijs, et al., Eur. Respir. J., 18, No. 1, 61–68 (2001).
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 12, pp. 617–620, December, 2007
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Geltser, B.I., Brodskaya, T.A., Kotelnikov, V.N. et al. Endothelial dysfunction of cerebral and major arteries during chronic obstructive disease. Bull Exp Biol Med 144, 768–771 (2007). https://doi.org/10.1007/s10517-007-0427-x
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DOI: https://doi.org/10.1007/s10517-007-0427-x