Mechanisms of bacterial resistance to macrolide antibiotics
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2022, Environmental Technology and InnovationPlant-derived nanotherapeutic systems to counter the overgrowing threat of resistant microbes and biofilms
2021, Advanced Drug Delivery ReviewsRefractory Helicobacter pylori gastritis: The hidden predictors of resistance
2019, Journal of Global Antimicrobial ResistanceCitation Excerpt :Resistance to the standard clarithromycin-based triple therapy is currently increasing and this has a significant negative impact on eradication rates [26]. Mutations at the binding sites of macrolides, mainly A2143 G, A2142 G and A2142C in the 23S rRNA in domain V, would impair the binding of macrolides to the 50S ribosomal subunit [27]. In the current study, the prevalence of clarithromycin resistance in non-responders with negative FAT was 24.5%.
Prevalence, antimicrobial resistance profile and comparison of methods for the isolation of salmonella in chicken liver from Argentina
2019, Food Research InternationalCitation Excerpt :Resistance to erythromycin (macrolide antibiotic) and penicillin has been reported as the most common resistance profile in retail meat products (Sallam, Mohammed, Hassan, & Tamura, 2014). Although, this could be due to improper usage or overuse of a particular antimicrobial causing resistance to occur, it is known that Gram-negative bacilli, as Salmonella sp., are usually intrinsically resistant to macrolide antibiotics (Chambers, 2006; Nakajima, 1999). On the other hand, low levels of intermediate resistances to streptomycin (22%) were observed.
Genetic characterisation of a whiB7 mutant of a Mycobacterium tuberculosis clinical strain
2015, Journal of Global Antimicrobial Resistance