Abstract:
Interstitial lung disease (ILD) in patients with myositis is defined by the presence of interstitial changes on radiographic examination. The reported prevalence of ILD varies from 0% to nearly 50%. However, only rarely has the pathological pattern of diffuse alveolar damage (DAD) associated with idiopathic inflammatory myopathy (IIM) been reported. We report five patients with IIM (one with dermatomyositis, one with polymyositis, and three with amyopathic dermatomyositis) and respiratory failure. Four underwent open lung biopsy with pathological proof of diffuse alveolar damage (DAD). Despite intensive immunosuppressive therapy, all of them died. In addition to the case reports, we discuss DAD in patients with IIM.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 18 June 2001 / Accepted: 6 March 2002
Rights and permissions
About this article
Cite this article
Lee, CS., Chen, TL., Tzen, CY. et al. Idiopathic Inflammatory Myopathy with Diffuse Alveolar Damage. Clin Rheumatol 21, 391–396 (2002). https://doi.org/10.1007/s100670200104
Published:
Issue Date:
DOI: https://doi.org/10.1007/s100670200104