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Bronchiolitis obliterans-organizing pneumonia (BOOP) in children with malignant disease

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Abstract

Four patients who had completed chemotherapy for malignant disease are presented. Unexpected findings of pulmonary infitlrates on chest radiographs of two patients and solitary and/or confluent nodules on CT in all four led to open lung biopsy. Histologic diagnosis in each case was bronchiolitis obliterans-organizing pneumonia (BOOP). This usually innocuous disorder can be differentiated histologically from the more severe pure bronchiolitis obliterans and should be considered in the differential diagnosis of pulmonary lesions associated with malignant disease.

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Supported in part by the National Cancer Institute, Cancer Center Support (CORE) grant P30CA21765 and by the American Lebanese Syrian Associated Charities

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Helton, K.J., Kuhn, J.P., Fletcher, B.D. et al. Bronchiolitis obliterans-organizing pneumonia (BOOP) in children with malignant disease. Pediatr Radiol 22, 270–274 (1992). https://doi.org/10.1007/BF02019856

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  • DOI: https://doi.org/10.1007/BF02019856

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