Regular ArticleAssessment of Nitric Oxide Production by Measurement of [15N]Citrulline Enrichment in Human Plasma Using High-Performance Liquid Chromatography–Mass Spectrometry☆
References (31)
- et al.
Br. J. Anaesth.
(1995) - et al.
Kidney Int.
(1995) - et al.
Lancet
(1995) - et al.
J. Chromatogr.
(1977) - et al.
J. Chromatogr. (Biomed. Appl.)
(1981) - et al.
Anal. Biochem.
(1983) - et al.
Metabolism
(1994) - et al.
Metabolism
(1982) - et al.
J. Chromatogr. A
(1995) - et al.
J. Am. Soc. Mass Spectrom.
(1995)
Trends Anal. Chem.
Anal. Biochem.
Nature
J. Clin. Invest.
Proc. Natl. Acad. Sci. USA
Cited by (23)
Plasma L-citrulline concentrations in L-arginine–supplemented healthy dogs
2017, Journal of Veterinary CardiologyMeasurement of in vivo nitric oxide synthesis in humans using stable isotopic methods: A systematic review
2011, Free Radical Biology and MedicineCitation Excerpt :In the following years, new methods were developed using different tracers (arginine, oxygen) [40–42] and different routes of administration (intravenous, intragastric, oral, inhalation) [40–43] and measuring different labeled species (citrulline, nitrate, nitrite) [43], as well as sampling from different accessible pools (plasma, urine) [40,41,44]. Seven studies used an arginine–citrulline protocol [38,40,45–49], 27 studies utilized an arginine–nitrate protocol [37,39–41,43,44,50–70], and only one study utilized the oxygen–nitrate protocol [42]. The intravenous primed-constant infusion was the most utilized administration route for the tracers [36,40–50,56,59,60,63,65–68], whereas a bolus intravenous administration of labeled l-arginine was employed in a few protocols [41,55,56,58,59,65,66].
Inaccuracies in selected ion monitoring determination of isotope ratios obviated by profile acquisition: nucleotide <sup>18</sup>O/<sup>16</sup>O measurements
2007, Analytical BiochemistryCitation Excerpt :The ability to detect such low enrichment may be extremely valuable for measuring the incorporation of isotopically enriched amino acids into proteins [31–33]. Overall, the results presented in Table 4 compare favorably with similar work for derivatized amino acids [34–36]. These studies used ESI with either ion trap or QMS and fast atom bombardment ionization-QMS.
Methods using stable isotopes to measure nitric oxide (NO) synthesis in the l-arginine/NO pathway in health and disease
2007, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life SciencesL-arginine-nitric oxide pathway in endstage reneal disease: Authors' reply
2002, American Journal of Kidney Diseases
- ☆
Waller, G. R.Dermer, O. C.