Experimental approaches

First-in-human evaluation of 18F-BMS-986327 as a novel PET tracer to assess lysophosphatidic acid receptor 1 (LPA1) target engagement in the lung
R Smith, D Donnelly, J Gallezot, Y Lu, B Murphy, P Cheng, J Kim, E Charles, S Du, D Holden, S Najafzadeh, H Gao, M Kapinos, J Ropchan, N Nabulsi, H Huang, A Fischer, R Carson

European Respiratory Journal Sep 2022, 60 (suppl 66) 1164; DOI: 10.1183/13993003.congress-2022.1164
Development of PRS-400, an inhaled Jagged-1 Anticalin protein for the treatment of muco-obstructive lung diseases
M Hagner, C Wurzenberger, J Peper-Gabriel, D Jaquin, N Quilitz, C Hechinger, T Jaquin, K Heinig, E Hansbauer, S Grüner, J Prassler, R S Bel Aiba, J Mayer, R Bharti, J A Wrennall, R Tarran, A Ray, S Wenzel, C Rothe, S A Olwill, G Matschiner, A Fysikopoulos

European Respiratory Journal Sep 2022, 60 (suppl 66) 931; DOI: 10.1183/13993003.congress-2022.931
Deep learning-based hybrid clinical decision support system algorithm for COVID-19 diagnosis via PCR graphics and Thorax CT images, preliminary data
E B Verdi, M Gok, D Dogan Mülazimoglu, M B Terzi, A Gurun Kaya, S Erol, O İsik, O U Guvendik, C Uzun, A H Elhan, Z C Karahan, A Azap, A Kaya, O Arikan, O Ozdemir Kumbasar

European Respiratory Journal Sep 2022, 60 (suppl 66) 1357; DOI: 10.1183/13993003.congress-2022.1357
Effects of salbutamol and ipratropium on human stem-cells derived cardiomyocytes’ function
M Scurek, S Klimovic, M Pesl, J Pribyl, D Kabanov, D Beckerova, M Bebarova, V Rotrekl, K Brat

European Respiratory Journal Sep 2022, 60 (suppl 66) 560; DOI: 10.1183/13993003.congress-2022.560
Anti-fibrotic effect and in vivo target engagement of Nintedanib administered by oral gavage or by a medicated diet in a bleomycin lung fibrosis model in the rat
M Trevisani, P Caruso, V Pitozzi, S Pontis, M G Pittelli, M Bonatti, G Villetti, M Civelli

European Respiratory Journal Sep 2022, 60 (suppl 66) 781; DOI: 10.1183/13993003.congress-2022.781
Harnessing the therapeutic power of secretomes to treat IPF
M Timaner, T Fishman-Jacob, B Pertzov, B Tadmor, J Laufer, M Kramer, Y Shaked

European Respiratory Journal Sep 2022, 60 (suppl 66) 427; DOI: 10.1183/13993003.congress-2022.427
Histological and structural effects of biodegradable polydioxanone stents in the rabbit trachea.
A Gimeno Diaz De Atauri, R Morante, A Usategui, M López, M C Luna, S Albi, J L Pablos, J L Anton-Pacheco Sanchez

European Respiratory Journal Sep 2022, 60 (suppl 66) 724; DOI: 10.1183/13993003.congress-2022.724
Can the generalizability problem of artificial intelligence be overcome?: Pneumothorax detection algorithm
E B Verdi, D Dogan Mülazimoglu, S Erol, A Gurun Kaya, M Yilmaz, A Turker, A M Ozbayoglu, O Isik, A Bostanoglu Karacin, O Velioglu Yakut, B M Yenigun, C Tasci, C Uzun, A H Elhan, A Kayi Cangir, O Ozdemir Kumbasar, A Kaya

European Respiratory Journal Sep 2022, 60 (suppl 66) 482; DOI: 10.1183/13993003.congress-2022.482
Machine Learning analysis of human pulmonary extracellular matrix architecture identifies disease-specific remodeling patterns
T K Lund, M J Emerson, O Willacy, C Madsen, R Reuten, C B Brøchner, A B Dahl, T H L Jensen, J T Erler, A E Mayorca-Guiliani

European Respiratory Journal Sep 2022, 60 (suppl 66) 787; DOI: 10.1183/13993003.congress-2022.787
A pilot trial for ozanimod therapy in hospitalized COVID-19 patients
D Marsolais, N Châteauvert, P Blais-Lecours, P Rola, T Nguyen, F Lellouche

European Respiratory Journal Sep 2022, 60 (suppl 66) 520; DOI: 10.1183/13993003.congress-2022.520

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