Animal models

A humanized animal model of pulmonary fibrosis based on cellular senescence
Fernanda Ines Hernandez Gonzalez, Federico Pietrocola, Neus Prats, Kathleen Meyer, Jose Alberto Lopez-Dominguez, Maria Isabel Muñoz, Miguel Rovira, Daniel Martinez, Jose Ramirez, Alvar Agusti, Rosa Faner, Jacobo Sellares, Manuel Serrano

European Respiratory Journal Sep 2020, 56 (suppl 64) 4470; DOI: 10.1183/13993003.congress-2020.4470
High-plex immunofluorescence single cell analysis of fibrotic murine lung on tissue microarrays
Francesca Ravanetti, Roberta Ciccimarra, Maddalena Bolognesi, Francesca Ruscitti, Luisa Ragionieri, Giorgio Cattoretti, Gino Villetti, Fabio Stellari

European Respiratory Journal Sep 2020, 56 (suppl 64) 4471; DOI: 10.1183/13993003.congress-2020.4471
HDAC6 inhibition and deletion reduce COPD symptoms in mice and human airway epithelia
Muriel Lizé, Sigrid Horstmann, Vera Düsterhus, Cornelia Wiedwald, Carolin Ebert, Annalisa Addante, Carlos Neideck, Stefan Frank, Florian Sohler, Markus Koch

European Respiratory Journal Sep 2020, 56 (suppl 64) 5033; DOI: 10.1183/13993003.congress-2020.5033
Single cell RNA analysis of cellular niche in normal and impaired late lung development
Ivana Mizikova, Maria Hurskainen, David Cook, Chanéle Cyr-Depauw, Flore Lesage, Noora Andresson, Emmi Helle, Laurent Renesme, Robert Jankov, Markku Heikinheimo, Barbara Vanderhyden, Bernard Thèbaud

European Respiratory Journal Sep 2020, 56 (suppl 64) 5242; DOI: 10.1183/13993003.congress-2020.5242
Blocking Focal adhesion kinase (FAK) protects against damage in a novel model of lymphocyte dominant lung injury
Danica Brister, Gurpreet Aulakah, Hong Zhang, Kamala Patel

European Respiratory Journal Sep 2020, 56 (suppl 64) 4469; DOI: 10.1183/13993003.congress-2020.4469
EPAC drives the anti-tussive effect of EP4 receptors on airway sensory nerves
Michael A. Wortley, Sara J Bonvini, John J Adcock, Eric D Dubuis, Sarah A Maher, Raymond B Penn, Maria G Belvisi, Mark A Birrell

European Respiratory Journal Sep 2020, 56 (suppl 64) 4562; DOI: 10.1183/13993003.congress-2020.4562
Protein truncating mutations in ATP13A3 promote pulmonary arterial hypertension
Ekaterina Legchenko, Bin Liu, James West, Peter Vangheluwe, Paul Upton, Nicholas Morrell

European Respiratory Journal Sep 2020, 56 (suppl 64) 4463; DOI: 10.1183/13993003.congress-2020.4463
Intranasal leptin prevents opioid-induced respiratory depression
Carla Freire, Huy Pho, Lenise Kim, Xin Wang, Jhansi Dyavanapalli, Stone Streeter, Thomaz Fleury-Curado, David Mendelowitz, Vsevolod Y. Polotsky

European Respiratory Journal Sep 2020, 56 (suppl 64) 4735; DOI: 10.1183/13993003.congress-2020.4735
The role of resident lung mesenchymal stromal cells in normal and aberrant lung development
Ivana Mizikova, Chanéle Cyr-Depauw, Flore Lesage, Maria Hurskainen, Arul Vadivel, Shumei Zhong, Bernard Thèbaud

European Respiratory Journal Sep 2020, 56 (suppl 64) 4472; DOI: 10.1183/13993003.congress-2020.4472
Hemodynamic and histological progression in the Sugen-Hypoxia Rat Model
Michel Corboz, Sandra Gagnon, Annie Bouchard, C Brodeur, Charles E Laurent, Dany Salvail, David Cipolla, Walter R Perkins, Richard W Chapman

European Respiratory Journal Sep 2020, 56 (suppl 64) 3563; DOI: 10.1183/13993003.congress-2020.3563

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