Animal models

Targeting aquaporin 1 reverses hypoxia-induced pulmonary hypertension in mice
Claudio Schuoler, Thomas Haider, Caroline Leuenberger, Johannes Vogel, Louise Ostergaard, Malcolm Kohler, Max Gassmann, Lars Huber, Matthias Brock

European Respiratory Journal Sep 2016, 48 (suppl 60) PA5104; DOI: 10.1183/13993003.congress-2016.PA5104
Erythropoietin recapitulates hemodynamic features of hypoxia-induced pulmonary hypertension in mice
Julien Becker, Emilie Peter-Thiebaut, Ghina Bou About, Lahcen El Fertak, Megane Denu, Hugues Jacobs, Patrick Reilly, Yann Herault, Laurent Monassier

European Respiratory Journal Sep 2016, 48 (suppl 60) PA5097; DOI: 10.1183/13993003.congress-2016.PA5097
Hemodynamic and anti-remodelling effect of the Rho kinase inhibitor Y-27632 in the monocrotaline pulmonary arterial hypertension rat model
Silvia Cantoni, Fiorella Pastore, Stefano Cavalli, Gessica Marchini, Gino Villetti, Romina Nassini, Francesco De Logu, Fabrizio Facchinetti

European Respiratory Journal Sep 2016, 48 (suppl 60) PA5100; DOI: 10.1183/13993003.congress-2016.PA5100
Antenatal sildenafil-simvastatin combination attenuates pulmonary hypoplasia and hypertension in nitrofen-induced congenital diaphragmatic hernia
Céline Dewachter, Martine Makanga, Hidekazu Maruyama, Emeline Hupkens, Jean-Luc Vachiery, Robert Naeije, Laurence Dewachter

European Respiratory Journal Sep 2016, 48 (suppl 60) PA5101; DOI: 10.1183/13993003.congress-2016.PA5101
Combining an epithelial repair factor and anti-fibrotic with a corticosteroid offers optimal treatment for the pathogenesis of allergic airways disease
Krupesh Patel, Chrishan Samuel, Simon Royce

European Respiratory Journal Sep 2016, 48 (suppl 60) PA4891; DOI: 10.1183/13993003.congress-2016.PA4891
Central role for the TRPV4-ATP-P2X3 axis in sensory nerve activation and the late asthmatic response
Mark Birrell, Sara J. Bonvini, Katie E. Baker, Bilel Dekkak, Anthony Ford, Montse Miralpeix, Gema Tarrason, Jaclyn A. Smith, Maria G. Belvisi

European Respiratory Journal Sep 2016, 48 (suppl 60) PA5069; DOI: 10.1183/13993003.congress-2016.PA5069
The effect of ASK1 inhibition on hypoxia-induced pulmonary artery fibroblast activation and associated paracrine effects on vascular smooth muscle cells
Kathryn Wilson, Korneilija Suveizdyte, John Liles, Grant Budas, Andrew Peacock, David Welsh

European Respiratory Journal Sep 2016, 48 (suppl 60) PA5095; DOI: 10.1183/13993003.congress-2016.PA5095
Alpha-7 nicotinic receptor stimulation reduces airway inflammation in a murine model of asthma
Fernanda Paula Roncon Santana, Cláudia Jeane Claudino de Pontes Miranda, Nathália Montouro Pinheiro, Adenir Perini, Luciana Chagas Caperuto, Iolanda de Fátima Lopes Calvo Tibério, Marco Antônio Maximo Prado, Milton de Arruda Martins, Vânia Ferreira Prado, Carla Máximo Prado

European Respiratory Journal Sep 2016, 48 (suppl 60) PA5066; DOI: 10.1183/13993003.congress-2016.PA5066
Roflumilast but not dexamethasone or fluticasone reduces neutrophilic airway inflammation and hyperreactivity in a murine influenza-induced asthma exacerbation model
Cornelia Tilp, Hannes Bucher, Eva Wex, Klaus Erb

European Respiratory Journal Sep 2016, 48 (suppl 60) PA4893; DOI: 10.1183/13993003.congress-2016.PA4893
A fixed combination of thyme and primula dry extracts normalizes goblet cell hyperplasia and MUC5AC formation in vivo and in vitro
Jan Seibel, Aldo Ammendola, Martin Lehner

European Respiratory Journal Sep 2016, 48 (suppl 60) PA4895; DOI: 10.1183/13993003.congress-2016.PA4895

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