Airway smooth muscle

Slow dissociation kinetics of LAMAs contribute to the functional interactions with LABAs
Reinoud Gosens, Carolina R.S. Elzinga, I. Sophie T. Bos, Herman Meurs, Loes E.M. Kistemaker

European Respiratory Journal Sep 2016, 48 (suppl 60) PA5058; DOI: 10.1183/13993003.congress-2016.PA5058
Monitoring local pulmonary cAMP levels: Combining precision cut lung slice (PCLS) and fluorescence resonance energy transfer (FRET) technologies in mice
Martina Schmidt, Haoxio Zuo, Wilfred Jelco Poppinga, Viacheslav Nikolaev

European Respiratory Journal Sep 2016, 48 (suppl 60) PA5055; DOI: 10.1183/13993003.congress-2016.PA5055
Pharmacological characterization of the mechanism of action leading to synergism between glycopyrronium bromide and indacaterol fumarate
Luigino Calzetta, Paola Rogliani, Ermanno Puxeddu, Josuel Ora, Francesco Facciolo, Maria Gabriella Matera, Mario Cazzola

European Respiratory Journal Sep 2016, 48 (suppl 60) PA5057; DOI: 10.1183/13993003.congress-2016.PA5057
Prostacyclin IP receptor activation blocks hyperosmolar-induced bronchoconstriction in isolated human small airways
Jesper Säfholm, Johan Bood, Sven-Erik Dahlén, Mikael Adner

European Respiratory Journal Sep 2016, 48 (suppl 60) PA5054; DOI: 10.1183/13993003.congress-2016.PA5054
Pharmacological characterization of the anti-oxidant activity of N-acetylcysteine in an ex vivo model of COPD exacerbation
Paola Rogliani, Josuel Ora, Luigino Calzetta, Gabriella Lucà, Maria Gabriella Matera, Mario Cazzola

European Respiratory Journal Sep 2016, 48 (suppl 60) PA5062; DOI: 10.1183/13993003.congress-2016.PA5062
Airway smooth muscle contractility is increased following coculture with fibrocytes
Ruth Saunders, Davinder Kaur, Fay Hollins, Andrew Wardlaw, Peter Bradding, Christopher Brightling

European Respiratory Journal Sep 2016, 48 (suppl 60) PA4654; DOI: 10.1183/13993003.congress-2016.PA4654
DP2/CRTh2 is expressed by ASM cells in asthma and its inhibition suppresses ASM migration
Ruth Saunders, Michael Biddle, Adam Wright, Latifa Chachi, Amanda Sutcliffe, Rachid Berair, Christopher Brightling

European Respiratory Journal Sep 2016, 48 (suppl 60) PA4653; DOI: 10.1183/13993003.congress-2016.PA4653
Computational modeling methods for simulating obstructive human lung diseases
Stavros Nousias, Aris Lalos, Konstantinos Moustakas, Antonios Lalas, Dimitrios Kikidis, Konstantinos Votis, Dimitrios Tzovaras, Omar Usmani, Fan Chung

European Respiratory Journal Sep 2016, 48 (suppl 60) PA4401; DOI: 10.1183/13993003.congress-2016.PA4401
Investigating the interaction between bronchoconstriction and cough in asthma
Imran Satia, Huda Badri, Mark Woodhead, Paul O'Byrne, Stephen Fowler, Jaclyn Smith

European Respiratory Journal Sep 2016, 48 (suppl 60) PA4192; DOI: 10.1183/13993003.congress-2016.PA4192
Inhaled roflumilast and tadalafil supress airway reactivity and inflammation in ovalbumin-sensitized guinea pigs
Juraj Mokry, Anna Urbanova, Martin Kertys, Ivana Medvedova, Peter Mikolka, Petra Kosutova, Daniela Mokra

European Respiratory Journal Sep 2016, 48 (suppl 60) PA4092; DOI: 10.1183/13993003.congress-2016.PA4092

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