Table 5– Standardised β-coefficients for correlations between concentrations of desmosines and lung function measures in subjects with and without chronic obstructive pulmonary disease (COPD)
No COPD#COPD
U-desmosinesP-desmosinesU-desmosinesP-desmosines
M/F n82/15278/13446/6944/62
FEV1-0.020.02-0.32***-0.22*
FEV1 % pred-0.030.06-0.42***-0.29*
FVC-0.050.03-0.29***-0.21*
FVC % pred-0.080.03-0.41***-0.29*
RV0.070.010.23*0.01
RV/TLC0.100.000.40***0.18
DL,CO-0.02-0.12*-0.25**-0.29**
  • Data adjusted for age, sex, height, body mass index and current smoking. Multiple linear regression was used with the lung function variable as the dependent variable. M: males; F: females; FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; RV: residual volume; TLC: total lung capacity; DL,CO: diffusing capacity of the lung for carbon monoxide. #: FEV1/FVC ≥0.70; : FEV1/FVC <0.70. *: p<0.05; **: p<0.01; ***: p<0.001.