Crude OR (95% CI) | Adjusted OR (95% CI)¶ | Adjusted OR (95% CI)¶ | |
FeNO | 1.03 (1.00–1.06) | 1.06 (1.01–1.11) | 1.06 (1.02–1.11) |
Birth weight | 0.79 (0.45–1.42) | 0.59 (0.27–1.3) | 0.6 (0.27–1.34) |
Smoke exposure | |||
Pre-natal only | 1.00 (0.27–3.65) | 0.56 (0.10–3.07) | 0.61 (0.12–3.14) |
Post-natal only | 1.19 (0.52–2.71) | 0.92 (0.36–2.37) | 0.9 (0.36–2.24) |
Pre- and post-natal | 2.33 (0.88–6.15) | 3.13 (1.07–9.12) | 2.9 (0.97–8.59) |
RTI within the first 6 months | 1.33 (0.69–2.54) | 0.96 (0.44–2.08) | 1.1 (0.53–2.28) |
URS within the first 6 months | 3.14 (0.40–24.4) | 4.22 (0.46–38.5) | 3.47 (0.37–32.6) |
Wheezing within the first 6 months | 4.29 (2.16–8.50) | 5.87 (2.62–13.15) | + |
LRS within the first 6 months | 6.27 (1.88–20.9) | + | 7.29 (2.05–25.9) |
FeNO: exhaled nitric oxide (NO) fraction; RTI: respiratory tract infections; URS: upper respiratory symptoms; LRS: lower respiratory symptoms; #: n=276; ¶: n=273, as RTI within the first 6 months had three missing values; adjusted for the factors listed as well as for sex, maternal atopy/atopic disease, age, Z-score for length, Z-score for weight, NO-free air use and ambient NO. +: variable not included in the model.