Table 4– Severity of disease in idiopathic pulmonary fibrosis (IPF) according to presence of hiatal hernia (HH) and use of anti-reflux medication in those with HH

IPF cohort	Subjects n	Age yrs	FVC % pred	D_{L,CO % pred}	CPI
HH absent	44	66.5	70.1±17.9	47.8±19.2	50.7±14.5
HH present	33	67.0	70.1±18.4	49.5±19.3	49.6±15.2
Anti-reflux medication used	19	66.8	73.7±17.2	55.7±19.9^#	44.8±15.0
Anti-reflux medication not used	14	67.2	65.1±19.5	40.9±15.0^#	56.0±13.5^#
p-value			ns	<0.03	<0.04

Data are presented as mean±sd, unless otherwise stated. None of the data were statistically significant. FVC: forced vital capacity; % pred: % predicted; D_L,CO: diffusing capacity of the lung for carbon monoxide; CPI: composite physiologic index; ns: nonsignificant. ^#: 15 of the 16 subjects were taking anti-reflux medication.