| Total | Success | TF | |
| Subjects n | 1236 | 1039 | 197 |
| Male sex | 691/1235 (55.9) | 582/1038 (56.0) | 109/197 (55.3) |
| Age yrs | 69.6±16.8 | 69.4±16.9 | 70.8±16.2 |
| BMI# kg·m−2 | 25.7±4.9 | 25.7±4.9 | 25.8±5.1 |
| Current smoker | 264/1194 (22.1) | 225/1003 (22.4) | 39/191 (20.4) |
| COPD | 341/1235 (27.6) | 295/1038 (28.4) | 46/197 (23.4) |
| LC | 31/1235 (2.5) | 24/1038 (2.4) | 7/197 (3.6) |
| CHF | 378/1235 (30.6) | 302/1038 (31.7) | 76/197 (38.6)¶ |
| DM | 443/1235 (35.9) | 361/1038 (44.5) | 82/197 (41.6) |
| Antibiotic pre-treatment | 144/1160 (12.4) | 126/983 (12.3) | 18/177 (9.2)¶ |
| CURB-65 score | |||
| 0 | 308 (24.9) | 274 (26.4) | 34 (17.3) |
| 1 | 549 (44.4) | 463 (44.6) | 86 (43.7) |
| 2 | 291 (23.5) | 228 (21.9) | 63 (31.9) |
| 3 | 78 (6.3) | 64 (6.1) | 14 (7.1) |
| 4 | 10 (0.8) | 10 (1.0) | 0 (0) |
| PSI score | |||
| 1 | 94 (7.6) | 80 (7.7) | 14 (7.1) |
| 2 | 162 (13.1) | 148 (14.2) | 14 (7.1) |
| 3 | 244 (19.7) | 216 (20.8) | 28 (14.2) |
| 4 | 536 (43.4) | 438 (42.2) | 98 (49.7) |
| 5 | 200 (16.2) | 157 (15.1) | 43 (21.8) |
Data are presented as n/N (%), mean±sd or n (%), unless otherwise stated. TF: treatment failure; BMI: body mass index; COPD: chronic obstructive pulmonary disease; LC: lung carcinoma; CHF: congestive heart failure; DM: diabetes mellitus; CURB-65: confusion of new onset, urea >7 mmol·L−1, respiratory rate of ≥30 breaths·min−1, blood pressure <90 mmHg systolic or diastolic blood pressure ≤60 mmHg, and age ≥65 yrs; PSI: pneumonia severity index. #: n=1055. p-value for all parameters >0.05, except ¶: p<0.01.