Table 6– Multivariate analyses of mortality and length of stay (LOS) with combinations of processes of care adjusted by hospital and pneumonia severity index

	In-hospital mortality		Mortality at 30 days		LOS
	OR (95% CI)	p-value	OR (95% CI)	p-value	OR (95% CI)	p-value
All population
Abx	0.61 (0.44–0.85)	0.004	0.63 (0.47–0.85)	0.003	0.76 (0.66–0.87)	0.001
Abx plus timing	0.61 (0.44–0.84)	0.003	0.67 (0.50–0.89)	0.007	0.80 (0.71–0.91)	0.001
Abx plus timing plus oxygen	0.64 (0.46–0.89)	0.009	0.70 (0.52–0.94)	0.02	0.79 (0.70–0.90)	0.001
Nonsevere sepsis
Abx	0.33 (0.16–0.65)	0.001	0.27 (0.15–0.49)	<0.001	0.76 (0.59–0.97)	0.03
Abx plus timing	0.47 (0.23–0.95)	0.03	0.44 (0.24–0.82)	0.009	0.73 (0.58–0.92)	0.007
Abx plus timing plus oxygen	0.54 (0.26–1.1)	0.09	0.52 (0.28–0.96)	0.03	0.64 (0.51–0.81)	0.001
Severe sepsis
Abx	0.75 (0.49–1.13)	0.2	0.86 (0.59–1.28)	0.4	0.82 (0.66–1.03)	0.08
Abx plus timing	0.60 (0.40–0.91)	0.01	0.69 (0.48–1.015)	0.06	0.94 (0.77–1.16)	0.6
Abx plus timing plus oxygen	0.62 (0.41–0.92)	0.02	0.70 (0.48–1.03)	0.07	0.91 (0.74–1.12)	0.3

Abx: antibiotic adherence to guidelines; Timing: first antibiotic dose <6 h.