| Parameters | 1st visit | 2nd visit | p-values¶ |
| Pulmonary function | |||
| FEV1 % pred | 88±15 | 85±21 | 0.27 |
| FVC % pred | 95±15 | 94±18 | 0.76 |
| FEV1/FVC % | 78 (67–87) | 74 (47–85) | 0.08 |
| FEF25–75% % pred | 68±26 | 62±29 | 0.09 |
| TLC % pred | 95±10 | 97±10 | 0.12 |
| RV/TLC % pred | 99 (71–138) | 97 (73–165) | 0.62 |
| DL,CO % pred | 72±14 | 73±17 | 0.68 |
| MBNW | |||
| LCI | 11.6±2.5 | 13.5±3.5 | 0.003 |
| Scond L−1 | 0.06 (0.02–0.17) | 0.07 (0.02–0.24) | 0.21 |
| Sacin L−1 | 0.28 (0.06–0.69) | 0.41 (0.08–1.07) | 0.007 |
| FOT % pred | |||
| Rrs | 113 (77–187) | 103 (73–259) | 0.50 |
| Xrs | 151 (9–792) | 172 (47–788) | 0.37 |
| eNO ppb | 7.5 (4.7–40.1) | 6.4 (3.6–16) | 0.46 |
| SGRQ total score | 15 (0–40) | 17 (1–63) | 0.23 |
| Symptoms score | 21 (0–73) | 17 (0–68) | 0.93 |
| Activity score | 29±25 | 33±27 | 0.45 |
| Impact score | 7 (0–22) | 6 (0–59) | 0.19 |
| cGVHD grade | 0 (0–3) | 1 (0–3) | 0.38 |
Data are presented as mean±sd or median (range), unless otherwise stated. FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; FEF25–75%: forced expiratory volume at 25–75% of FVC; TLC: total lung capacity; RV: residual volume; DL,CO: diffusing capacity of the lung for carbon monoxide; MBNW: multiple breath nitrogen washout; LCI: lung clearance index; Scond: index of conductive airways heterogeneity; Sacin: index of diffusive airways heterogeneity; FOT: forced oscillation technique; Rrs: respiratory system resistance; Xrs: respiratory system reactance; eNO: exhaled nitric oxide; SGRQ: St George’s Respiratory Questionnaire; cGVHD: chronic graft-versus-host disease. #: the second visits were performed 10±6 months after the first visits; ¶: paired t-test or Wilcoxon signed rank test depending on the distribution of the differences.