Parameters | Univariate correlations | Independent predictors# | ||
r | p-value | Partial r2 | p-value | |
Pulmonary function % pred | ||||
FEV1 | -0.58 | <0.001 | 0.24 | 0.02 |
FVC | -0.44 | 0.01 | ||
FEV1/FVC | rs = -0.30 | 0.10 | ||
FEF25–75% | -0.41 | 0.02¶ | ||
TLC | 0.20 | 0.25 | ||
Log RV/TLC | 0.41 | 0.02 | ||
DL,CO | 0.07 | 0.69 | ||
MBNW | ||||
Log LCI | 0.62 | <0.001 | ||
Scond | 0.45 | 0.01+ | ||
Log Sacin | 0.62 | <0.001§ | 0.18 | 0.04ƒ |
FOT % pred | ||||
Rrs | rs = -0.01 | 0.97 | ||
Log Xrs | r=0.51 | 0.002+ | ||
eNO (log) | r=0.05 | 0.77 |
FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; FEF25–75%: forced expiratory volume at 25–75% of FVC; TLC: total lung capacity; RV: residual volume; DL,CO: diffusing capacity of the lung for carbon monoxide; MBNW: multiple breath nitrogen washout; LCI: lung clearance index; Scond: index of conductive airways heterogeneity; Sacin: index of diffusive airways heterogeneity; FOT: forced oscillation technique; Rrs: respiratory system resistance; Xrs: respiratory system reactance; eNO: exhaled nitric oxide. #: independent predictors of time post transplant in multiple regression model including significant parameters (in italics) from univariate analyses; ¶: insignificant after removing the two patients with longest time post-transplant; +: insignificant after removing the two patients with highest measured values; §: after correction for age and smoking history (confounding factors), the correlation was still highly significant (r=0.55, p=0.001); ƒ: Sacin corrected for confounding factors was used in the multiple regression model. Italics indicates significant univariate correlations after correction for multiple comparisons.