Table 3– Correlation analysis of T-bet (T-box, expressed in T-cell) expression with mRNA expression of selected sarcoidosis-associated genes
GeneSarcoidosis versus controls p-valueCorrelation with T-bet expression[Ref.]#
Spearman's coefficientp-value
IFNG0.00002**0.660<0.001**[3, 30, 31]
IL-2R/IL-15Rβ0.01**0.753<0.001**[10, 22]
CCL20.4100.1690.200[18]
CCL50.0002**0.627<0.001**[18, 19]
CXCL90.0007**0.2780.033*[14, 15]
CXCL100.0006**0.3530.006**[14, 16, 17]
CXCL110.013*0.2590.052[14, 15]
CCR2-variant A0.003**0.2320.116[20]
CCR2-variant B0.2100.4060.003*
CCR50.001**0.2090.149[10, 21]
CXCR30.0007**0.738<0.001**[4, 10, 14]
CXCR60.00004**0.4550.001**[4]

  • #: selected references about the association of corresponding molecules with sarcoidosis. *: p<0.05; **: p<0.01.