Table 2– Distribution of asthma control and the clinical features used to define asthma control among subjects with current physician-diagnosed asthma according to ADRB2 Gly16Arg genotype in the European Community Respiratory Health Survey (ECRHS) II population#
Gly/GlyGly/ArgArg/Arg
Subjects221277106
Asthma control
 Controlled67 (42.95)67 (42.95)22 (14.10)
 Noncontrolled138 (33.17)196 (47.12)82 (19.71)
  Partially controlled80 (33.33)109 (45.42)51 (21.25)
  Uncontrolled58 (32.95)87 (49.43)31 (17.61)
Features used to define asthma control
 Diurnal symptoms in the previous 3 months ≥1 per week53 (24.2)82 (29.9)29 (27.4)
 Asthma attacks in the previous 3 months
  Yes64 (29.9)95 (35.1)35 (33)
  ≥1 per week27 (12.2)33 (11.9)12 (11.3)
 Nocturnal symptoms in the previous 3 months69 (31.5)99 (36.3)29 (27.6)
 Activity limitation in the previous 3 months51 (24.3)70 (27)23 (23)
 SABAs in the previous 3 months
  >2 per week60 (29.8)76 (29.6)33 (32.7)
 Use of oral steroids in the previous 3 months
  Yes13 (6)20 (7.2)10 (9.5)
  Short courses or continuous10 (4.6)11 (4)5 (4.8)
 FEV1 <80% pred at ECRHS II32 (15)37 (14.1)20 (19.2)
 Emergency department visit in the previous 12 months10 (4.6)18 (6.5)7 (6.6)
 Hospitalisation in the previous 12 months2 (0.9)2 (0.7)0 (0)
  • Data are presented as n or n (%). SABA: short-acting β2-agonist; FEV1: forced expiratory volume in 1 s; % pred: % predicted. #: n=604.