Table 3– Prognostic value of the four prognostic independent covariates from the study by Paesmans et al. [4]

Characteristic	Derivation series^#		Validation series^¶
	HR (95% CI)	p-value	HR (95% CI)	p-value
Karnofsky performance status ≥80	0.73 (0.60–0.86)	<0.001	0.56 (0.46–0.70)	<0.0001
Female sex	0.71 (0.54–0.94)	0.02	0.83 (0.66–1.02)	0.08
Limited disease	0.66 (0.57–0.78)	<0.001	0.45 (0.38–0.51)	<0.0001
Neutrophils ≤75%	0.80 (0.67–0.96)	0.05	0.68 (0.57–0.82)	<0.0001

HR: hazard ratio. ^#: n = 763, 45 censored observations; ^¶: n = 693, 47 censored observations.