Total | Males | Females | ||||
Sarcoidosis | Healthy | Sarcoidosis | Healthy | Sarcoidosis | Healthy | |
Exercise capacity | ||||||
6MWD m | 576±124*** | 723±80 | 607±118*** | 747±74 | 518±115*** | 679±73 |
6MWD % pred | 79.5±16.3 | 81.3±15.8 | 76.3±16.9 | |||
Reduced 6MWD# | 45.2 | 3.2 | 41.3 | 2.5 | 52.3 | 4.5 |
Muscle force | ||||||
HGF lbs | 94.4±33.3 | 97.9±27.8 | 110.7±25.9 | 115.5±15.1 | 64.1±22.4 | 65.9±12.5 |
HGF % pred | 96.3±27.0 | 95.8±22.5 | 97.1±34.0 | |||
Reduced HGF# | 15.4 | 3.2 | 16.3 | 2.5 | 14.0 | 4.5 |
EFMS N | 219.5±72.2* | 242.8±72.4 | 255.8±58.8* | 287.0±47.9 | 150.4±35.8 | 162.6±22.9 |
EFMS % pred | 90.3±21.0 | 89.1±20.5 | 92.5±22.0 | |||
Reduced EFMS# | 12.3 | 3.2 | 10.0 | 2.5 | 16.7 | 4.5 |
QPT Nm | 80.9±36.1*** | 101.3±30.6 | 95.6±34.0*** | 118.4±23.0 | 53.9±21.1*** | 70.2±13.3 |
QPT % pred | 79.3±29.1 | 80.8±28.7 | 76.7±30.0 | |||
Reduced QPT# | 27.0 | 6.5 | 22.8 | 5.0 | 34.9 | 9.1 |
HPT Nm | 61.5±26.6*** | 75.3±23.0 | 71.4±26.0*** | 86.3±18.7 | 43.2±16.2* | 55.3±15.3 |
HPT % pred | 81.3±29.7 | 82.9±30.1 | 78.3±29.1 | |||
Reduced HPT# | 18.0 | 0 | 20.3 | 0 | 14.0 | 0 |
PI,max cmH2O | -82.5±29.5 | NA | -90.7±30.7 | NA | -67.7±20.1 | NA |
PI,max % pred | 82.5±28.5 | 80.2±25.9 | 86.6±32.8 | |||
Reduced PI,max# | 43.1 | 44.3 | 41.0 |
Data are expressed as mean±sd or %. 6MWD: 6-min walking distance; % pred: % predicted; HGF: handgrip force; EFMS: elbow flexor muscle strength; QPT: quadriceps peak torque; HPT: hamstrings peak torque; PI,max: maximal inspiratory pressure; NA: not applicable. #: percentage of subjects below the mean results minus 2sd of the control group. *: p<0.05; ***: p<0.001.