Table 4– Risk factor and health outcome definition: visible mould and allergic rhinitis
First author [ref.]LocationDefinition of exposureDefinition of outcomeAge yrsChildren nOR central estimate (95% CI)Type of estimate
Antova [15]Pollution and the Young Study, multiple locationsVisible mouldHay fever ever6–12570991.35 (1.18–1.53)aOR
Mould ever1.48 (1.34–1.62)aOR
Recent mould1.47 (1.35–1.61)aOR
Dong [17]ChinaVisible mouldDD allergic rhinitis (ever)6–13107841.21 (0.97–1.50)aOR
Brunekreef [21]USAMould/mildew (age 7–11 yrs)Hay fever (8–12 yrs)7–1246251.57 (1.31–1.87)aOR
Dong [22]ChinaVisible mouldDD allergic rhinitis1–639451.20 (0.72–1.99)aOR
Ibargoyen-Roteta [44]SpainMould on walls (age 1 yr)Allergic rhinoconjunctivitis (age 5–8 yrs)1–833601.34 (0.64–2.79)aOR
Chen [25]TaiwanMould patchesDD allergic rhinitis7–1214521.48 (1.03–2.12)aOR
Li [26]TaiwanVisible mould/mildewAllergic rhinitis symptoms8–1213401.27 (0.96–1.68)aOR
Biagini [45]USA (Cincinnati Childhood Allergy and Air Pollution Study)Visible mouldAllergic rhinitis1495
Low versus none1.2 (0.6–2.5)aOR
High versus none3.2 (0.7–14.8)aOR
Stark [46]USAMould/mildew (age 1 yr)DD allergic rhinitis or hay fever (age 5 yrs)1–54051.28 (0.74–2.22)cHR
Koskinen [47]FinlandMould presentRhinitis≤7578.01 (0.77–83.82)aOR
7–151471.77 (0.69–4.53)aOR
Li [35]TaiwanVisible mouldAllergic rhinitis7–15453.50 (1.00–12.34)aOR
  • aOR: adjusted odds ratio; DD: physician-diagnosed; cHR: crude hazard ratio. Data in bold were included within the meta-analysis.