Table 2– Risk factor and health outcome definition: visible mould and asthma
First author [ref.]LocationDefinition of exposureDefinition of outcomeAge yrsChildren nOR central estimate (95% CI)Type of estimate
Antova [15]Pollution and the Young Study, multiple locationsVisible mouldAsthma ever6–1257099 (pooled)1.35 (1.201.51)aOR
Mould ever1.36 (1.19–1.56)aOR
Recent mould1.23 (1.07–1.41)aOR
Dales [16]CanadaNo. of mould sitesDD asthma5–813495
0 versus 11.40 (1.16–1.68)cOR
0 versus 21.67 (1.272.19)cOR
Dong [17]ChinaVisible mouldDD asthma (ever)6–13107841.54 (1.22–1.94)aOR
Current asthma1.69 (1.152.48)aOR
Ponsonby [18]Tasmania, AustraliaMould in child’s room i.r.Asthma763781.26 (0.87–1.81)aOR
Mould (excl. bathroom) p.r.1.20 (0.961.51)aOR
Spengler [19]RussiaPresence of mouldsDD asthma8–1259512.82 (1.634.88)aOR
Asthma symptoms1.98 (1.53–2.55)aOR
Freeman [20]USAAny mouldDD asthma8.1–10.946341.54 (1.271.87)aOR
Any mould<62403.30 (1.576.97)aOR
Brunekreef [21]USAMould or mildew (age 7–11 yrs)DD Asthma8–1246251.27 (0.931.74)aOR
Dong [22]ChinaVisible mouldDD asthma1–639451.56 (1.132.16)aOR
Current asthma1.89 (1.22–2.94)aOR
Brunekreef [23]The NetherlandsVisible mould (1987)Asthma6–1210511.12 (0.393.38)aOR
Visible mould (1989)Asthma33441.53 (1.042.28)aOR
Warman [24]USAVisible mould on wallsDD asthma5–1117723.26 (2.384.45)cOR
Visible mould on walls, ceilings or windowsDD asthma2.66 (2.04–3.48)cOR
Chen [25]TaiwanMould patchesDD asthma7–1214521.55 (0.783.09)aOR
Asthma symptoms1.56 (0.90–2.69)aOR
Li [26]TaiwanVisible mould/mildewDD asthma8–1213401.12 (0.72–1.74)aOR
Zheng [27]ChinaMould or fungiDD Asthma6–101209
Family ceiling1.8 (1.1–2.9)aOR
Child’s bedroom1.8 (1.0–3.2)aOR
Maier [28]USAVisible mouldDD asthma5–99251.3 (0.9–1.9)cOR
Dijkstra [29]The NetherlandsDamp stains and mouldAsthma6–127751.56 (0.50–4.87)cOR
Tischer [30]Germany and The NetherlandsVisible mould (Germany)DD asthma63581.03 (0.26–4.16)aOR
Visible mould (The Netherlands)3321.14 (0.48–2.70)aOR
Verhoeff [31]The NetherlandsVisible mouldDD Asthma ever6–12516
Living room p.r.2.95 (1.34–6.25)cOR
Child’s bedroom p.r.1.88 (0.74–4.78)cOR
Living room i.r.1.83 (0.81–4.13)cOR
Child’s bedroom i.r.0.99 (0.31–3.14)cOR
Dales [32]CanadaEver mould/mildewDD asthma104030.91 (0.42–1.95)aOR
Pekkanen [33]FinlandVisible mouldDD Asthma1–73621.24 (0.73–2.11)aOR
Mould spots living room4.01 (1.12–14.32)aOR
Visible mould living room1.95 (0.69–5.47)aOR
Fagbule [34]NigeriaMould growthCurrent asthma5.52800.48 (0.30–0.79)aOR
Li [35]TaiwanVisible mouldAsthma7–15461.02 (0.39–2.69)aOR
  • aOR: adjusted odds ratio; DD: physician-diagnosed; cOR: crude odds ratio; p.r.: parental reported; i.r.: inspector reported. Data in bold were included within the meta-analysis.