Table 6– Proportions of patients with notable values for plasma potassium, blood glucose, pulse rate, blood pressure and QTc interval (Fridericia’s formula)
IndacaterolTiotropium
Plasma potassium <3.0 mmol·L−10/7780/776
Blood glucose >9.99 mmol·L−126/778 (3.3)20/776 (2.6)
High pulse rate#2/792 (0.3)0/799
High systolic blood pressure7/792 (0.9)5/799 (0.6)
High diastolic blood pressure+6/792 (0.8)13/799 (1.6)
QTc interval
 Absolute value males/females >450/470 ms23/793 (2.9)25/799 (3.1)
 Absolute value >500 ms0/7931/799 (0.1)
 Increase 30–60 ms36/788 (4.6)48/794 (6.0)
 Increase >60 ms2/788 (0.3)0/794
  • Data are presented as n/N (%). #: >130 bpm, or ≥120 bpm and ≥15 bpm increase from baseline; : >200 mmHg, or ≥180 mmHg and ≥20 mmHg increase from baseline; +: >115 mmHg, or ≥105 mmHg and ≥15 mmHg increase from baseline.