STEMI | Severe CAP | ||
Current practice | Future model | ||
First medical contact and emergency care flow | Emergency medical system | Not established | Emergency medical system |
Working diagnosis: history, clinical symptoms, 12-lead ECG | Working diagnosis: history, clinical symptoms, chest radiography | Working diagnosis: history, clinical symptoms, chest radiography | |
Biomarker (troponin) | Biomarker (procalcitonin, adrenomedullin) | Biomarker (procalcitonin, adrenomedullin) | |
Pre-hospital and early in-hospital care | Reperfusion | Antibiotics | Antibiotics |
Oxygen and/or ventilatory support | Oxygen and/or ventilatory support | ||
Early goal-directed therapy | |||
Timescales: door-to-balloon, door-to-needle | Not established | Timescales: door-to-antibiotic, door-to-fluid resuscitation, 6-h timescale of severe sepsis | |
Management of the later in-hospital course | Cardiac failure Thrombosis and embolism Intraventricular thrombus and emboli Pericarditis Late ventricular arrhythmias Post-infarction angina and ischaemia | Pneumonic: parapneumonic effusion, empyema, abscess | Pneumonic: parapneumonic effusion, empyema, abscess |
Nonpneumonic: others | Nonpneumonic: others | ||
Risk assessment | Myocardial viability Risk of arrhythmia and sudden death | Not defined | Unknown |
Rehabilitation and pre-discharge advice | Psychological and socioeconomic | Not defined | Psychological and socioeconomic |
Lifestyle advice | Lifestyle advice | ||
Physical activity | Physical activity | ||
Secondary prevention | Lifestyle habits: smoking, diet weight control, physical activity | Not defined | Lifestyle habits: smoking, diet, dietary supplements, weight control, physical activity |
Drugs: antiplatelet and anticoagulant treatment, statins, β-blockers, angiotensin-converting enzyme or angiotension receptor blockers, aldosterone blockade | Not defined | Unknown | |
Control of atherosclerotic risk factors: blood pressure, diabetes, lipid profile, influenza vaccination | Not defined | Unknown | |
Influenza vaccination | Influenza vaccination | ||
Pneumococcal vaccination | Pneumococcal vaccination |