| Symptom algorithm | Exacerbations# n | Incidence exacerbations·person-yr−1 (95% CI) | Exacerbations n (% total) (% patients with an exacerbation) | Clustering type n (% total) | Recovery time days | Anthonisen classificaton n (% total) | Total symptom count n | Concurrence with reported and treated events | ||||||||
| 0 | 1 | >1 | Initial | Relapsed | Recurrent | I | II | III | Reported events n (%) | Treated events n (%) | Missed admissions¶ n | |||||
| 1. | 119 | 1.7 (1.4–2.1) | 81 (59) | 25 (18) (45) | 31 (23) (55) | 69 (58) | 13 (11) | 50 (42) | 14 (7–22) | 27 (23) | 38 (32) | 54 (45) | 57 (27–94) | 62 (52) | 31 (26) | 1 |
| 2. | 119 | 1.7 (1.4 –2.1) | 81 (59) | 25 (18) (45) | 31 (23) (55) | 69 (58) | 13 (11) | 50 (42) | 14 (7–22) | 27 (23) | 38 (32) | 54 (45) | 57 (27–94) | 62 (52) | 31 (26) | 1 |
| 3. ≥1 | 132 | 1.9 (1.6–2.3) | 73 (53) | 30 (22) (47) | 34 (25) (53) | 75 (57) | 14 (11) | 57 (43) | 13 (7–22) | 27 (20) | 39 (30) | 66 (50) | 51 (23–91) | 62 (47) | 31 (24) | 1 |
| 4. ≥2 | 54 | 1.5 (0.6–1.0) | 105 (77) | 20 (15) (63) | 12 (8) (37) | 35 (65) | 2 (4) | 19 (35) | 14 (8–21) | 27 (50) | 27 (50) | 70 (42–125) | 41 (76) | 22 (41) | 5 | |
Data are presented as median (interquartile range), unless otherwise stated. The symptom alogrithms are: 1. Modified Anthonisen; 2. Modified Anthonisen+fever; 3. ≥1 major symptom; 4. ≥2 major symptoms. #: relapsed exacerbations excluded (original exacerbation and relapse are considered as the same event); ¶: hospital and emergency room visits missed.