Table 1– Clinical and laboratory findings in a 6-yr-old girl with community-acquired pneumonia and clarithromycin-induced Mycoplasma pneumoniae macrolide resistance
CharacteristicDay 0Day 4Day 10Day 15Day 25Day 30
Axillary temperature# °C40.539.038.3ApyrexiaApyrexiaApyrexia
Respiratory rate breaths·min−1605552452524
Sp,O2 %858885909598
Heart rate beats·min−11351391401108276
Blood pressure mmHg90/6093/6188/5891/6295/6590/60
Chest radiographyMultiple “ground- glass” infiltratesNE“Ground-glass” opacificationsNESignificantly improvedNE
Chest CT scanNEBilateral infiltrates, with “ground-glass” opacificationsNENENENE
White blood cell count cells·μL−110100NE118601128049006790
Neutrophils %79NE82844160
CRP mg·dL−114.27.17.13.90.8<0.3
ESR mm first hour53NE48NENE11
Bacterial findingsM. pneumoniae DNA in nasopharyngeal swabM. pneumoniae DNA in nasopharyngeal swabM. pneumoniae DNA in nasopharyngeal swab and BALM. pneumoniae DNA in nasopharyngeal swabM. pneumoniae DNA in nasopharyngeal swabNegative
 GenotypeVariant 2aVariant 2aVariant 2aVariant 2aVariant 2aNE
 Mutation of 23S rRNANoneNoneA2063GA2063GA2063GNE
Viral findingsNegativeNegativeNegativeNegativeNegativeNegative
Antibiotic therapyAmpicillin/sulbactam and clarithromycinMeropenem and teicoplanin and clarithromycinMeropenem and teicoplanin and clarithromycinMeropenem and teicoplanin and ciprofloxacinCiprofloxacinEnd of ciprofloxacin
Supportive O2 therapy L·min−18664NRNR
  • Sp,O2: arterial oxygen saturation measured by pulse oximetry; CT: computed tomography; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; rRNA: ribosomal RNA; BAL: bronchoalveolar lavage; NE: not evaluated; NR: not required. #: peak day value; : in room air.