Table 1– Baseline parameters of the study population
ParameterIncident cohortPrevalent cohortp-value
Subjects n69181
Time from diagnosis of PAH days (range)2.2±0.5 (0–14)217±19 (16–1008)
Time from onset of dyspnoea days (range)489±95 (10–3643)933±112 (17–14053)0.027
Age yrs53.2±1.848.6±1.10.04
Female n (%)42 (61)128 (71)0.07
NYHA functional class II/III/IV13/46/034/126/21
Peak V′O2 mL·kg−1·min−113.6±0.6#12.4±0.40.08
pa mmHg50±1.656±1.10.004
ra mmHg7.1±0.68.5±0.40.07
PVR dyn·s·cm−51133±791372±520.02
CI L·min−1·m−21.97±0.081.86±0.040.2
Sv,O2 %61.7±1.158.6±0.70.02
  • Data are presented as mean±sem or mean±sem (range), unless otherwise stated. PAH: pulmonary arterial hypertension; NYHA: New York Heart Association; V′O2: oxygen uptake; pa: mean pulmonary artery pressure; ra: mean right arterial pressure; PVR: pulmonary vascular resistance; CI: cardiac index; Sv,O2: mixed venous oxygen saturation. #: n = 54; : n = 146.