Table 4– Pattern of wheeze in the past 3 months
EP with BPDEP without BPDControl
Subjects n341534
Wheeze during the day2478
Wheeze with colds29**134
Wheeze without colds1576
Wheeze with exercise26*76
SOB with exercise59**2021#
  • Data are presented as %, unless otherwise stated. EP: extreme pre-term; BDP: bronchopulmonary dysplasia; SOB: shortness of breath. Exact test for comparison between the three subgroups: *: p<0.05; **: p<0.01. #: objective assessments of physical activity showed that all children undertook considerably less physical activity than current recommendations of at least 60 min of moderate-vigorous physical activity per day which may explain why 21% of controls experience SOB with exercise.