Table 1– Changes in exercise capacity and patient-reported outcomes during pre-trial rehabilitation and from randomisation to 6-month follow-up
MeasurementBeginning of rehabilitationEnd of rehabilitation6 months after randomisationChange from beginning to end of rehabilitationChange from randomisation to 6-month follow-up
Patients n12171217100112171001
6MWD m348.0±95.1370.8±96.2377.0±99.9#22.8±53.6-4.6±68.7#
MCEC W36.0±21.138.9±21.642.2±22.62.9±11.00.9±13.9
SGRQ total score56.5±13.053.0±12.748.4±16.8-3.5±9.9-4.3±14.3
 SGRQ symptoms58.3±19.356.0±19.954.3±20.9-2.3±16.2-1.4±19.2
 SGRQ activities81.9±12.779.4±13.471.7±20.0-2.5±10.8-7.2±18.6
 SGRQ impact41.4±16.736.9±15.633.1±18.6-4.4±13.4-3.5±16.1
SOBQ total score65.6±19.062.7±18.455.2±24.1-3.0±13.6-6.7±20.8
  • Data are presented as mean±sd, unless otherwise stated. 6MWD: 6-min walk distance; MCEC: maximal cycle exercise capacity; SGRQ: St George's Respiratory Questionnaire; SOBQ: University of California San Diego Shortness of Breath Questionnaire. #: n = 907; : n = 905.