Controls | Asymptomatic smokers | COPD no GCS | COPD GCS | |
Subjects n | 29 | 17 | 16 | 16 |
Age yrs | 60.2±7.9 | 60.4±6.8 | 62.1±5.0 | 66.0±8.6 |
FEV1 % pred | 104.9±14.5 | 98.2±13.0 | 67.5±10.9 | 46.4±17.0 |
GOLD stage | ||||
I | 1 | 0 | ||
II | 13 | 6 | ||
III | 2 | 8 | ||
IV | 0 | 2 | ||
Plasma IL-1β pg·mL−1 | 0.31±0.38 | 0.21±0.28 | 0.28±0.34 | 0.29±0.34 |
Plasma sIL-1Ra pg·mL−1 | 51.2±50.0 | 37.3±40.0 | 37.5±23.2 | 22.2±17.1 |
Data are presented as mean±sd, unless otherwise stated. COPD: chronic obstructive pulmonary disease, GCS: glucocorticosteroids; FEV1: forced expiratory volume in 1 s; % pred: % predicted; GOLD: Global Initiative for Chronic Obstructive Lung Disease; IL: interleukin; sIL-1Ra: secreted IL-1 receptor antagonist.