Table 2– Results of receiver operating characteristic (ROC) curve analysis
Prediction of mortalityPrediction of any adverse outcomesPrediction of ICU admissionPrediction of complications
AUC (95% CI)p-value versus PSIp-value versus CURB-65AUC (95% CI)p-value versus PSIp-value versus CURB-65AUC (95% CI)p-value versus PSIp-value versus CURB-65AUC (95% CI)p-value versus PSIp-value versus CURB-65
PSI score0.79 (0.75–0.84)0.0080.67 (0.62–0.71)0.260.65 (0.59–0.71)0.70.50 (0.40–0.60)0.93
CURB-65 score0.72 (0.65–0.78)0.0080.64 (0.60–0.69)0.260.64 (0.58–0.70)0.700.50 (0.41–0.60)0.93
Initial PCT levels0.60 (0.52–0.67)<0.001<0.010.66 (0.61–0.71)0.820.630.69 (0.64–0.75)0.270.140.69 (0.58–0.77)<0.01<0.01
Peak PCT levels0.65 (0.57–0.72)<0.010.130.69 (0.65–0.74)0.400.10.73 (0.67–0.79)0.0350.010.7 (0.59–0.80)<0.01<0.01
Combined initial PCT/PSI score0.80 (0.74–0.85)0.910.71 (0.66–0.76)<0.010.72 (0.67–0.78)<0.010.68 (0.58–0.77)<0.01
Combined initial PCT/CURB-65 score0.73 (0.66–0.79)0.430.70 (0.65–0.75)0.0080.71 (0.65–0.77)<0.010.68 (0.58–0.78)<0.01
  • ICU: intensive care unit; AUC: area under the ROC curve; PSI: Pneumonia Severity Index;; CURB-65: confusion, urea >7 mmol·L−1, respiratory frequency ≥30 breaths·min−1, low blood pressure (systolic value <90 mmHg or diastolic value ≤60 mmHg) and age ≥65 yrs; PCT: procalcitonin.