KC pg·mL−1 | MIP-2 pg·mL−1 | IL-1β pg·mL−1 | IL-6 pg·mL−1 | TNF pg·mL−1 | |
H+/S+ | 11224±778 | 22822±11200 | 1949±472 | 859±156 | 1368±302 |
H+/S- | 6115±1605* | 32113±12403 | 3411±1122 | 1271±236 | 1944±648 |
H-/S+ | 11198±682 | 34712±11590 | 2674±490 | 1328 ± 176 | 1755±395 |
H-/S- | 6954±1321* | 4245±1035 | 855±154* | 1106±129 | 1978±425 |
Data are presented as mean±sem. Chimeric mice were infected with 4×104 colony-forming units of Klebsiella pneumoniae 6 weeks after bone marrow transplantation. 24 h later, mice were sacrificed, lungs were removed and keratinocyte-derived chemokine (KC), macrophage inflammatory protein (MIP)-2, interleukin (IL)-1β, IL-6 and tumour necrosis factor (TNF) were determined using ELISA. n = 7–8 mice per group. H: haematopoietic; S: structural. *: p<0.05 versus wild-type levels (H+/S+).