Table 6– Prognostic factors for in-hospital mortality of patients with acute exacerbation
ParametersOR (95% CI)p-value
Univariate logistic analysis
 Age1.022 (0.969–1.078)ns
 Male sex1.455 (0.543–3.895)ns
 Disease duration0.994 (0.977–1.011)ns
 Steroid with/without cytotoxic agent use#0.828 (0.353–1.943)ns
  Duration1.142 (0.932–1.399)ns
  Last dose1.034 (0.990–1.081)ns
 Duration of dyspnoea0.939 (0.902–0.978)0.003
 Documented fever2.364 (0.799–6.989)ns
 Sputum production1.705 (0.684–4.252)ns
Pa,O2/FI,O20.989 (0.983–0.996)0.001
 CRP1.087 (1.009–1.172)0.029
  Total cells0.998 (0.992–1.003)ns
  Lymphocytes0.905 (0.826–0.992)0.033
  Neutrophils1.055 (0.996–1.118)0.070
Multivariate logistic analysis
 CRP2.467 (1.030–5.911)0.043
 BAL lymphocytes0.869 (0.737–1.024)0.093
  • Pa,O2: arterial oxygen tension; FI,O2: inspiratory oxygen fraction; CRP: C-reactive protein; BAL: bronchoalveolar lavage; ns: nonsignificant. #: within 30 days prior to rapid deterioration; : steroid treatment.