Table 5– Comparison of the clinical features of the patients with acute exacerbation (AE) and the bilateral infection at the time of rapid deterioration (RD)
Age yrs65.3±7.966.1±7.6ns
Males69 (76.7)30 (81.1)ns
Disease duration months16.5±24.529.5±34.70.014
Steroid with/without cytotoxic agent use#56 (62.2)20 (54.1)ns
 Duration months3.4±3.84.5±5.2ns
 Last dose mg18.8±13.218.4±15.0ns
Duration of dyspnoea days11.2±12.56.1±7.40.030
Initial symptoms
 Documented fever18 (20.0)19 (51.4)0.001
 Sputum production63 (70.0)31 (83.8)ns
CRP mg·dL−18.3±6.814.7±9.8<0.001
 Total cells·mm−3292±168349±342ns
 Lymphocytes %19.7± 19.68.1±7.50.041
 Neutrophils %22.9±19.955.2±28.90.001
  • Data are presented as n, mean±sd or n (%), unless otherwise stated. CRP: C-reactive protein; Pa,O2: arterial oxygen tension; FI,O2: inspiratory oxygen fraction; BAL: bronchoalveolar lavage; ns: nonsignificant. #: within 30 days prior to RD; : steroid (prednisolone) treatment.