Table 3– Sputum microbiology, antibiotic treatment and hospital admissions prior to referral to the adult clinic and associations with case status (long-term survival)
AllCasesControlsOR (95% CI)Wald test p-value
Subjects n23078152
Microbiology#
Staphylococcus aureus
  No148 (84.6)61 (91.0)87 (80.6)1.000.06
  Yes27 (15.4)6 (9.0)21 (19.4)0.40 (0.15–1.06)
Pseudomonas aeruginosa
  No151 (85.8)65 (95.6)86 (79.6)1.000.01
  Yes25 (14.2)3 (4.4)22 (20.4)0.18 (0.05–0.65)
Haemophilus influenzae
  No159 (90.3)63 (92.7)96 (88.9)1.000.42
  Yes17 (9.7)5 (7.4)12 (11.1)0.63 (0.21–1.92)
Oral antibiotics+
 No oral antibiotics54 (28.6)8 (11.4)46 (38.7)1.00§<0.01
 Only oral antibiotics63 (33.3)40 (57.1)23 (19.3)8.31 (3.02–22.88)
 Oral and other antibiotics72 (38.1)22 (31.4)50 (42.0)1.05 (0.34–3.18)
Aerosol antibiotics+
 No138 (69.0)59 (83.1)79 (61.2)1.00§<0.01
 Yes62 (31.0)12 (16.9)50 (38.8)0.16 (0.06–0.48)
Intravenous antibiotics+
 No124 (63.3)52 (73.2)72 (57.6)1.00§<0.01
 Yes72 (36.7)19 (26.8)53 (42.4)0.15 (0.05–0.42)
Previous hospital admissions n
 016 (8.3)13 (18.8)3 (2.4)1.00§0.01
 1–5178 (91.8)56 (81.2)122 (97.6)0.17 (0.04–0.70)
  • Data are presented as n (%), unless otherwise stated. ORs were derived from weighted logistic regression models. #: acquisition before 16 yrs of age; : analysis was limited to those attending from 16 yrs of age; +: analysis was limited to those attending from 15 yrs of age; §: OR adjusted for age at initial assessment.