OR (95% CI) | p-value | |
Underlying and demographic conditions | ||
Male sex | 4.81 (1.80–12.55) | <0.01 |
Age | 1.02 (0.99–1.04) | 0.08 |
Alcoholism | 3.79 (1.67–8.56) | <0.01 |
Tobacco consumption | 2.03 (0.94–4.45) | 0.07 |
Charlson score | 1.25 (1.09–1.44) | <0.01 |
Immunocompromise | 2.51 (1.04–6.08) | 0.05 |
Severity at admission | ||
Pa,O2/FI,O2 <250 | 6.20 (2.75–13.93) | <0.001 |
Multilobar involvement | 5.59 (2.38–13.59) | <0.001 |
Need for vasopressors | 4.15 (1.90–9-07) | <0.001 |
Need for mechanical ventilation | 3.53 (1.70–7.79) | 0.01 |
Severity of illness scores | ||
PSI class V | 14.91 (5.08–43.9) | <0.001 |
ATS/IDSA criteria | 6.65 (2.88–15.36) | <0.001 |
Antibiotic resistance | ||
Penicillin | ||
Macrolide | 4.43 (2.02–9.72) | <0.01 |
Microbiology | ||
H serotypes | 1 | |
O serotypes | 2.36 (0.63–9.05) | 0.2 |
L serotypes | 10.34 (2.94–36.5) | <0.001 |
Antibiotic therapy | ||
Monotherapy | 1.94 (0.90–4.16) | 0.1 |
Combination therapy | 1 |
H serotypes (reference category): 1, 5 and 7F. L serotypes: 3, 6A, 6B, 8, 19F and 23F. O serotypes: non-L, non-H serotypes. Pa,O2: arterial oxygen tension; FI,O2: inspiratory oxygen fraction; PSI: Pneumonia Severity Index; ATS: American Thoracic Society; IDSA: Infectious Diseases Society of America.