H serotypes | L serotypes | O serotypes | |
Subjects | 93 | 78 | 123 |
Age yrs | 54.2±20.0¶ | 66.4±17.2 | 65.2±18.5 |
Comorbidities | |||
Cardiopathy | 10 (10.7)+ | 23 (29.4) | 30 (24.3) |
Lung Disease | 18 (19.3)§ | 21 (26.9) | 44 (35.7) |
Liver disease | 7 (7.5)+ | 15 (19.2) | 24 (19.5) |
Renal disease | 5 (5.3) | 7 (8.9) | 16 (13) |
Immunocompromise | 6 (6.4) | 12 (15.3) | 20 (16.2) |
Charlson score | 1.04±1.6¶ | 2.44±2.3 | 2.49±2.2 |
Pa,O2/FI,O2 <250 | 24 (25.8) | 35 (44.8)## | 42 (34) |
Need for vasopressors | 15 (16.1) | 21 (26.9)## | 13 (10.5) |
Multilobar involvement | 42 (45.1) | 42 (53.8) | 46 (37.3) |
ICU admission | 20 (21.5) | 25 (32) | 24 (19.5) |
Mechanical ventilation | 12 (12.9) | 20 (25.6)## | 17 (13.8) |
Severe pneumonia# | 25 (26.8) | 40 (51.2)## | 43 (34.9) |
Pleural effusion | 33 (35.4) | 23 (29.4) | 32 (26) |
Complicated parapneumonic effusion or empyema | 16 (17.2)¶ | 5 (6.4) | 5 (4) |
Combination therapy | 44 (47) | 49 (63) | 63 (51) |
PSI class V | 17 (18.2)ƒ | 47 (60.2) | 49 (39.8) |
LOS for survivors | 12.72±12.1 | 17.2±16.7 | 14.21±11.1 |
30-day mortality | 3 (3.2) | 20 (25.6)¶¶ | 9 (7.3) |
Data are presented as n, mean±sd or n (%), unless otherwise stated. H serotypes: 1, 5 and 7 F. L serotypes: 3, 6A, 6B, 8, 19F and 23F. O: Other serotypes. Pa,O2: arterial oxygen tension; FI,O2: inspiratory oxygen fraction; ICU: intensive care unit; PSI: Pneumonia Severity Index; LOS: length of stay. #: Pneumonia was considered severe when patients met at least one of two major American Thoracic Society (ATS)/Infectious Diseases Society of America (IDSA) criteria or three of the nine minor ATS/IDSA criteria 1. ¶: p<0.001 between group H and the other two groups. +: p<0.05 between group H and the other two groups (Chi-squared test). §: p<0.05 between groups H and O. ƒ: p<0.05 between three groups. ##: p<0.05 between group L and the other two groups. ¶¶: p<0.001 between group L and the other two groups.