Table 2– Grade 3–4 toxicity after chemotherapy, surgery and radiotherapy
ChemotherapySurgeryRadiotherapy
Subjects574638
Haematological and biochemical
 Leukopenia1 (1.8)
 Anaemia1 (1.8)4 (8.7)
 Neutropenia9 (15.5)
 Hyponatraemia3 (5.2)
 Hyperkalaemia2 (3.4)
Anorexia1 (2.2)2 (5.3)
Dysphagia1 (2.6)
Nausea2 (5.3)
Vomiting1 (2.6)
Fatigue1 (1.8)2 (5.3)
Infection2 (3.6)1 (2.2)
Pneumonia2 (4.3)
Pain3 (5.4)3 (6.5)1 (2.6)
Dyspnoea2 (3.6)5 (4.7)1 (2.6)
Renal toxicity1 (1.8)
Septic shock1 (1.8)
Thromboembolism2 (3.6)
Atrial fibrillation1 (1.8)4 (8.7)
Cardiac other4 (8.7)
Retinal detachment1 (1.8)
Empyema1 (2.2)
Haemorrhage requiring reoperation2 (4.3)
Bronchopleural fistula2 (4.3)
Post-pneumonectomy pulmonary oedema2 (2.2)
Vascular (other)1 (8.7)
Other#4
  • Data are presented as n or n (%). #: includes post-operative stroke (n = 1), obstipation (n = 1) and haemorrhage not requiring reoperation (n = 2).