Overall | IG | CG | p-value | |
Subjects n | 120 | 60 | 60 | |
Males/females n | 105/15 | 54/6 | 51/9 | 0.58 |
Age yrs | 68.1±1.40 | 66.1±1.46 | 70.2±1.15 | 0.07 |
BMI kg·m−2 | 28.60±0.41 | 28.20±0.60 | 29.02±0.66 | 0.35 |
Current smoker | 37 (30.8) | 17 (28.3) | 20 (33.3) | 0.69 |
Ex-smoker | 76 (63.3) | 39 (65.0) | 37 (61.6) | 0.84 |
Smoking pack-yrs | 68±3.79 | 62.4±5.03 | 73.6±5.62 | 0.14 |
Consumption score | ||||
Vegetable | 1.22±0.3 | 1.26±0.4 | 1.18±0.4 | 0.30 |
Fresh fruit/juice | 1.42±0.4 | 1.22±0.4 | 1.48±0.5 | 0.70 |
Meat | 1.87±0.2 | 1.90±0.3 | 1.87±0.4 | 0.70 |
Fish | 1.05±0.2 | 1.11±0.3 | 1.02±0.4 | 0.60 |
Alcohol | 1.61±0.3 | 1.30±0.3 | 1.18±0.3 | 0.17 |
Chronic cough | 89 (74) | 45 (75) | 44 (72) | 0.61 |
Chronic sputum | 86 (71) | 39 (65) | 47 (78) | 0.39 |
Chronic dyspnoea | 52 (56) | 28 (46) | 24 (40) | 0.75 |
FEV1 L | 1.82±0.06 | 1.93±0.10 | 1.71±0.07 | 0.09 |
FEV1 % pred | 64.28±1.58 | 64.39±2.32 | 64.17±2.19 | 0.94 |
FVC L | 2.75±0.09 | 2.90±0.14 | 2.59±0.11 | 0.09 |
FVC % pred | 74.64±1.66 | 75.71±2.47 | 73.50±2.22 | 0.52 |
FEV1/FVC % pred | 64.67±0.96 | 64.77±1.14 | 64.57±1.56 | 0.92 |
PEF L·min−1 | 4.62±0.17 | 4.98±0.28 | 4.26±0.21 | 0.10 |
Sa,O2 % | 95.58±0.24 | 95.20±0.33 | 95.96±0.34 | 0.81 |
Charlson index | 2.58±0.12 | 2.39±0.16 | 2.77±0.17 | 0.11 |
Arthritis | 1 (0.8) | 0 (0.0) | 1 (1.7) | 1 |
Cardiac failure | 25 (20.8) | 10 (16.7) | 15 (25.0) | 0.36 |
Coronary disease | 33 (27.5) | 16 (26.7) | 17 (28.3) | 1 |
Diabetes | 22 (18.3) | 8 (13.3) | 14 (23.3) | 0.23 |
Diseases of the liver | 2 (1.7) | 0 (0.0) | 2 (3.3) | 0.49 |
Hypertension | 69 (57.5) | 32 (53.3) | 37 (61.7) | 0.46 |
Nephropathy | 3 (2.7) | 2 (1.7) | 1 (3.3) | 1 |
Stroke | 8 (6.7) | 4 (6.7) | 4 (6.7) | 1 |
Data are presented as mean±sem or n (%), unless otherwise indicated. The Mann–Whitney test or Fisher's exact test was used as appropriate for comparisons between groups. IG: intervention group; CG: control group; BMI: body mass index; FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; PEF: peak expiratory flow; Sa,O2: arterial oxygen saturation.