Clinical outcome | Cohort subgroup | Subjects | SAE-IgE | |
OR (95% CI) | p-value | |||
Asthma | Whole population | 1337 (140) | 1.95 (1.39–2.76) | <0.001 |
Atopics | 799 (113) | 1.47 (1.01–2.16) | 0.048 | |
Non-atopics | 537 (27) | 1.83 (0.61–5.52) | 0.286 | |
Rhinoconjunctivitis | Whole population | 1336 (527) | 1.93 (1.50–2.48) | <0.001 |
Atopics | 798 (413) | 1.21 (0.91–1.62) | 0.188 | |
Non-atopics | 537 (114) | 1.79 (0.93–3.44) | 0.080 | |
BHR | Whole population | 1286 (236) | 2.06 (1.54–2.76) | <0.001 |
Atopics | 767 (182) | 1.53 (1.11–2.12) | 0.010 | |
Non-atopics | 518 (54) | 2.41 (1.04–5.58) | 0.041 |
Data for subjects are presented as total cases in analysis (cases positive for clinical outcome). Odds ratio is per log10 (kU·L−1). BHR: bronchial hyperresponsiveness.