Table 1– Patient characteristics stratified by treatment step
TreatmentNumber of RxPatientsMean age yrsFemalesCurrent smokers#Peak flowDistribution of Rx over different stepsRx for any asthma medication in next 6 months
Inhaled SABALABAICS
SABA only (step 1)1,895,096 (25.0)381,375 (75.1)41.759.041.679.034.40.00.073.5
Standard dose ICS only372,814 (4.9)71,867 (14.1)44.462.718.982.30.00.010.882.4
Regular inhaled preventer therapy (step 2)1,812,758 (23.9)20,2041 (39.8)40.559.335.579.228.40.038.687.5
Standard dose ICS + LABA + SABA (step 3)336,578 (4.4)38,220 (7.5)43.461.135.177.44.419.67.193.9
Standard dose ICS + other asthma medication, no LABA (step 3b)165,324 (2.2)17,717 (3.5)54.759.939.769.71.90.02.896.5
LABA + no ICS (step 3c)318,286 (4.1)35,058 (6.9)45.760.624.675.82.718.70.093.9
Standard dose ICS and LABA, no SABA180,843 (2.4)26,475 (5.2)46.661.923.380.40.012.64.591.1
High dose ICS + LABA, (step 4)720,847 (9.5)48,953 (9.6)45.860.227.575.06.844.417.194.1
High dose ICS + other asthma medications, no SABA and no LABA (step 4b)9,177 (0.1)1,679 (0.3)55.064.126.974.10.00.00.396.6
High dose ICS + SABA, no LABA – (step 4c)512,172 (6.7)45,698 (9.0)44.959.330.274.98.00.011.293.8
High dose ICS only79,883 (1.1)14,989 (3.0)47.661.718.680.40.00.02.388.1
Regular oral corticosteroids (step 5)174,051 (2.3)17,671 (3.5)56.864.029.064.50.91.30.896.3
Other/unclassified1,016,770 (13.3)125,652 (24.7)47.760.129.270.112.53.54.491.2
  • Data are presented as n (%) or %, unless otherwise stated. Rx: prescription; SABA: short-acting β2-agonist; LABA: long-acting β2-agonist; ICS: inhaled corticosteroid. #: smoking status was not recorded in one out of three of the patients, and past smokers were also not included in this calculation. : for any asthma medication.