Normal CL,s/normal DL,CO | Low CL,s | Low DL,CO | Low CL,s/low DL,CO | |
Subjects n | 476 | 141 | 123 | 90 |
Cases in stages I/II/III % | 33.8/56.5/9.7 | 23.4/61.7/14.9 | 19.5/61.0/19.5 | 5.6/66.7/33.3 |
Females % | 41.6 | 68.1 | 40.7 | 47.8 |
Age yrs | 38.2±9.5 | 48.0±11.1 | 35.9±8.5 | 45.7±12.9 |
Weight kg | 79.8±15.5 | 75.6±13.6 | 77.2±16.1 | 74.6±14.8 |
Height cm | 172.0±9.3 | 163.2±8.8 | 174.6±9.3 | 167.3±11.0 |
Ever-smokers % | 40.7 | 35.5 | 54.5 | 47.8 |
Smoking exposure# pack-yrs | 7.5±8.1 | 9.6±9.9 | 8.6±9.0 | 15.7±18.0 |
FVC % pred | 103.9±11.3 | 95.2±12.4 | 93.4±10.8 | 78.4±12.2 |
VC % pred | 112.3±13.9 | 108.2±17.2 | 100.9±12.9 | 87.5±15.7 |
TLC % pred | 108.4±11.8 | 102.1±11.7 | 99.7±12.9 | 86.2±14.1 |
RV/TLC % pred | 92.9±16.1 | 98.1±16.2 | 95.4±20.0 | 103.1±20.6 |
FEV1/FVC % | 80.0±6.4 | 79.6±6.7 | 80.2±7.2 | 78.6±8.2 |
Subjects with abnormal FEV1/FVC % | 11.1 | 7.8 | 12.2 | 20.0 |
FEF25–75% % pred | 88.1±25.6 | 78.8±29.1 | 81.6±25.6 | 63.4±31.1 |
Subjects with abnormal FEF25–75% % | 14.9 | 22.7 | 23.6 | 50.0 |
Data are presented as mean±sd, unless otherwise stated. FVC: forced vital capacity; % pred: % predicted; VC: vital capacity; TLC: total lung capacity; RV: residual volume; FEV1: forced expiratory volume in 1 s; FEF25–75%: forced expiratory flow at 25–75% FVC. #: ever-smokers only.