Table 1– Baseline characteristics for the entire population, survivors and nonsurvivors
Entire groupSurvivorsNonsurvivors
Subjects90 (100)62 (69)28 (31)
Age yrs59±1258±1458±15
Males47 (52)29 (47)18 (64)
Creatinine μmol·L−188.5±26.287.7±26.091.9±27.3
Pulmonary function
DL,CO % pred38.0±15.939.7±16.634.0±13.7
 FVC % pred75.3±22.378.6±21.9*68.1±21.7*
 TLC % pred77.1±19.879.3±20.271.7±18.1
Pa,O2 kPa9.2±2.39.5±2.98.5±2.0
6-min walk test#
 End test Sp,O2 %83.3±8.884.2±9.182.5±9.3
 6-min walk distance m271±127277±130258±123
Brain natriuretic peptide pmol·L−111 (1.4–377)9 (3–193.8)22 (1.4–377)
Echocardiography
 RVSP mmHg+49.9±21.746.9±21.3*59.2±19.1*
 RAP mmHg8.3±3.98.0±4.18.8±3.4
 Pulmonary acceleration time ms96.8±26.9109.3±32.3102.2±31.2
 Fractional shortening %36.8±9.237.6±9.835.1±7.9
  • Data are presented as n (%), mean±sd or median (range). DL,CO: diffusing capacity of the lung for carbon monoxide; % pred: % predicted; FVC: forced vital capacity; TLC: total lung capacity; Pa,O2: arterial oxygen tension; Sp,O2: arterial oxygen saturation measured by pulse oximetry; RVSP: right ventricular systolic pressure; RAP: right arterial pressure. #: n = 55; +: n = 63. *: p<0.05 (unpaired t-test); : p<0.05 (Wilcoxon's rank sum test).