Variable | Sham | CIH | Sham-AA | CIH-AA | ||||
Mean±sem | n | Mean±sem | n | Mean±sem | n | Mean±sem | n | |
MABP mmHg | 111±4 | 15 | 138±3*** | 16 | 117±6## | 9 | 109±6### | 10 |
fC beats·min−1 | 427±17 | 15 | 403±14 | 16 | 394±15 | 9 | 386±17 | 10 |
VT mL·kg−1 | 4.4±0.5 | 14 | 3.6±0.4 | 22 | 3.4±0.2 | 11 | 3.6±0.2 | 11 |
fR breaths·min−1 | 78±6 | 14 | 74±3 | 22 | 80±4 | 11 | 78±3 | 11 |
V′I mL·min−1·kg−1 | 369±58 | 14 | 273±37 | 22 | 286±26 | 11 | 291±39 | 11 |
Basal fx Hz | 48±6 | 8 | 81±11** | 11 | 42±4## | 5 | 47±4## | 10 |
Sham-AA: control rats that received oral ascorbic acid; CIH-AA: rats supplemented with oral ascorbic acid during the exposure to CIH; MABP: mean arterial blood pressure; fC: cardiac frequency; VT: tidal respiratory volume; fR: respiratory frequency; V′I: minute inspiratory volume; fx: carotid body chemosensory activity. ***: p≤0.001 versus sham; **: p≤0.01 versus sham; ###: p≤0.001 versus CIH: ##: p≤0.01 versus CIH.