Demographic and clinical characteristics of rheumatoid arthritis-associated interstitial lung disease patients
Population | p-value | |||||
RA-UIP | RA-non-UIP | IPF | Overall | RA-non-UIP# | IPF# | |
Subjects n | 20 | 62 | 51 | |||
Age yrs | 69±6 | 65±10 | 72±9 | 0.001 | 0.15 | 0.08 |
Male sex | 55 | 50 | 75 | 0.03 | 0.70 | 0.11 |
Duration of RA yrs | 7 (3–30) | 2 (0–9) | NA | NA | 0.03 | NA |
Ever-smoker | 55 | 77 | 76 | 0.12 | 0.05 | 0.07 |
FVC % pred | 66±25 | 70±20 | 69±21 | 0.72 | 0.39 | 0.63 |
DL,CO % pred | 50±22 | 48±21 | 41±16 | 0.10 | 0.56 | 0.07 |
Data are presented as mean±sd, percentage or median (interquartile range), unless otherwise indicated. RA-UIP: usual interstitial pneumonia (UIP) pattern in patients with rheumatoid arthritis (RA); RA-non-UIP: non-UIP pattern in patients with RA; IPF: idiopathic pulmonary fibrosis; FVC: forced vital capacity; DL,CO: diffusing capacity of the lung for carbon monoxide; NA: not applicable; % pred: percentage of the predicted value. #: versus RA-UIP.