Table 1—

General characteristics of children with obstructive sleep apnoea(OSA) and healthy controls

ControlMild OSAModerate-to-severe OSA
Subjects n11510634
Age yrs7.81±1.447.65±1.557.20±1.69
Males %55.760.461.8
Caucasian %64.361.355.9
BMI Z-score1.15±1.22**1.32±1.39§1.97±1.1##
Log AHI-0.39±0.27** (0.40±0.27)0.30±0.20§ (2.23±1.02)1.13±0.27ƒ (16.60±11.05)
Sa,O2 nadir %92.2±5.2**89.7±5.2§81.1±9.4##
Respiratory arousal index events·h−15.2±7.36.9±7.88.3±5.2
Total cholesterol# mg·dL−1159.3±25.1*168.2±27.2181.3±44.8ƒ
HDL cholesterol# mg·dL−150.1±10.252.6±11.649.0±12.7
LDL cholesterol# mg·dL−192.6±22.9*100.2±22.6110.1±37.5
Triglycerides# mg·dL−182.7±43.1*76.1±35.1111.2±78.0
Peak hyperaemic response# s36.8±21.136.6±19.641.9±24.4
Log IL-6 (pg·mL−1)-0.22±0.51* (0.98±0.95)-0.13±0.45 (1.16±1.26)0.13±0.30ƒ (1.78±1.63)
Log hsCRP+ (mg·dL−1)-0.17±0.41** (1.16±1.57)-0.10±0.44 (1.51±2.35)0.27±0.36## (2.54±2.02)
Log MRP8/14 (μg·mL−1)-0.11±0.34** (1.02±0.85)-0.00±0.31§ (1.27±0.87)0.18±0.23## (1.73±0.92)
  • Data are presented as mean±sd, unless otherwise stated. Log data are presented as log (absolute) mean±sd. BMI; body mass index; AHI: apnoea/hypopnoea index; Sa,O2: arterial oxygen saturation; HDL: high-density lipoprotein; LDL: low-density lipoprotein; IL: interleukin; hsCRP: high sensitivity C-reactive protein; MRP8/14: myeloid-related protein 8/14. #: data were acquired in 134 children; : includes 72 children; +: includes 112 children; §: p<0.05, controls versus mild OSA; ƒ: p<0.05, controls versus moderate-to-severe OSA; ##: p<0.01, controls versus moderate-to-severe OSA. *: p<0.05, **: p<0.01, differences between three groups (ANOVA test).