Table 1—

Time from onset of symptoms and inflammatory response

	Early-comers group <48 h	Late-comers group ≥48 h	p-value
Subjects n	13	19
TNF-α pg·mL⁻¹	19.1±8.5	35.5±26	0.03
IL-1β pg·mL⁻¹	6.7±9	3.4±4	0.2
IL-8 pg·mL⁻¹	79.5±112	175±573	0.5
IL-6 pg·mL⁻¹	3569±6646	2122±3149	0.4
IL-10 pg·mL⁻¹	44±40	23±28	0.09
IL-1ra pg·mL⁻¹	8754±7734	7379±7182	0.6
CRP pg·mL⁻¹	130±85	327±131	<0.001
SAA pg·mL⁻¹	678±509	984±391	0.025
Fibrinogen mg·dL⁻¹	6±1.8	9±2	0.001
Albumin mg·dL⁻¹	40±5	36±5	0.043

Data are presented as mean±sd, unless otherwise indicated. TNF: tumour necrosis factor; IL: interleukin; CRP: C-reactive protein; SAA: serum amyloid A.