FVC decline | HR (95% CI) | p-value |
7% threshold | 1.76 (0.86–3.60) | 0.12 |
6% threshold | 2.08 (1.05–4.13) | 0.04 |
5% threshold | 2.31 (1.19–4.50) | 0.01 |
4% threshold | 2.11 (1.11–4.00) | 0.02 |
3% threshold | 1.43 (0.75–2.68) | 0.27 |
Significant (p<0.05) relationships are shown, with hazard ratios (HR), expressing the change in risk of mortality between those with change and those without change (with 95% CI). The prognostic significance of thresholds of 4 and 5% did not differ. By contrast, a 3% threshold was always inferior to 4 and 5% thresholds.