Prevalence of serial decline at 6 months in idiopathic pulmonary fibrosis(IPF) and non-specific interstitial pneumonia (NSIP) patients
| IPF | NSIP | p-value | |
| Subjects n | 84 | 72 | |
| DL,CO | |||
| Significant decline >15% | 23 (27) | 13 (18) | 0.13 |
| Marginal decline 7.5–15% | 23 (27) | 4 (6) | <0.001 |
| Marginal or significant decline >7.5% | 46 (55) | 17 (24) | <0.001 |
| FVC | |||
| Significant decline >10% | 22 (26) | 13 (18) | 0.19 |
| Marginal decline 5–10% | 19 (23) | 7 (10) | 0.06 |
| Marginal or significant decline >5% | 41 (49) | 20 (28) | <0.01 |
Data are presented as n (%), unless otherwise stated. A higher proportion of patients with IPF had either significant or marginal decline compared with those with NSIP (p<0.001). DL,CO: diffusing capacity of the lung for carbon monoxide; FVC: forced vital capacity.