Table 1—

Number and percentage of patients and healthy controls with immunoglobulin(Ig)G and IgM anti-endothelial cell antibodies (AECA) directed towards surface antigens on human umbilical vein endothelial cells (HUVEC)

Patients nImmunoglobulin type
IPAH 29 (17 females)18 (62.1)13 (44.8)
CTD-associated PAH 18 (17 females)14 (77.8)11 (61.1)
SSc 51 (41 females)22 (43.1)21 (41.2)
DM II 40 (28 females)5 (12.5)7 (17.5)
HC 40 (22 females)13 (32.5)8 (20.0)
  • Data are presented as n or n (%), unless otherwise stated. IPAH: idiopathic pulmonary arterial hypertension; CTD-associated PAH: connective tissue disease-associated pulmonary arterial hypertension; SSc: systemic sclerosis; SLE: systemic lupus erythematosus; MCTD: mixed connective tissue disease; lSSc: limited cutaneous SSc; dSSc: diffuse cutaneous SSCs; DM II: diabetes mellitus type II; HC: healthy controls.