Number and percentage of patients and healthy controls with immunoglobulin(Ig)G and IgM anti-endothelial cell antibodies (AECA) directed towards surface antigens on human umbilical vein endothelial cells (HUVEC)
| Patients n | Immunoglobulin type | ||
| IgG | IgM | ||
| IPAH | 29 (17 females) | 18 (62.1) | 13 (44.8) |
| CTD-associated PAH | 18 (17 females) | 14 (77.8) | 11 (61.1) |
| SSc | 14 | 10 | 9 |
| SLE | 2 | 2 | 1 |
| MCTD | 2 | 2 | 1 |
| SSc | 51 (41 females) | 22 (43.1) | 21 (41.2) |
| lSSc | 42 | 20 | 17 |
| dSSc | 9 | 2 | 4 |
| DM II | 40 (28 females) | 5 (12.5) | 7 (17.5) |
| HC | 40 (22 females) | 13 (32.5) | 8 (20.0) |
Data are presented as n or n (%), unless otherwise stated. IPAH: idiopathic pulmonary arterial hypertension; CTD-associated PAH: connective tissue disease-associated pulmonary arterial hypertension; SSc: systemic sclerosis; SLE: systemic lupus erythematosus; MCTD: mixed connective tissue disease; lSSc: limited cutaneous SSc; dSSc: diffuse cutaneous SSCs; DM II: diabetes mellitus type II; HC: healthy controls.