Table 1—

Patient characteristics

Subjects n51
Age yrs62.6±9.1
Female sex10 (19.6)
Stage
 IIA2 (3.9)
 IIB3 (5.9)
 IIIA19 (37.3)
 IIIB9 (17.6)
 IV18 (35.3)
Diagnosis
 Adenocarcinoma40 (78.4)
 NSCLC11 (21.6)
Diagnostic procedure
 EBUS-TBNA26 (51.0)
 Bronchoalveolar lavage1 (2.0)
 Bronchial biopsy5 (9.8)
 Pericardial fluid1 (2.0)
 Bone metastasis2 (3.9)
 Surgery16 (31.4)
Lymph node metastasis by EBUS-TBNA36 (70.6)
 Adenocarcinoma29 (56.9)
 Unspecified NSCLC7 (13.7)
Metastatic lymph node region sampled
  4R10 (19.6)
  4L2 (3.9)
  722 (43.1)
  Lobar node2 (3.9)
EGFR analysis feasible
 Adenocarcinoma EBUS-TBNA samples20 (39.2)
 NSCLC EBUS-TBNA samples6 (11.8)
 Other biopsy/cytology samples25 (49.0)
EGFR mutation status
 Present5 (9.8)
  Exon 192 (3.9)
  Exon 213 (5.9)
 Wild-type46 (90.2)
Mutation identified only in EBUS-TBNA sample2 (3.9)
  • Data are presented as mean±sd or n (%), unless otherwise indicated. NSCLC: nonsmall cell lung cancer; EBUS-TBNA: endobronchial ultrasound-guided transbronchial needle aspiration; EGFR: epidermal growth factor receptor.